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Stigmasterol alleviates central precocious puberty by targeting the IGF-1/PI3K/Akt/mTOR signaling pathway and modulating the Kisspeptin/GnRH axis.

This is a source-metadata record last found in a complete check on Sep 25, 2026. It is not a Pependium assessment of safety or effectiveness. Check the original sources for current details, corrections and full methods.
Source status: Exact-ID Europe PMC status checked Sep 26, 2026. No retraction or correction publication-type marker was listed in that response. This does not rule out other updates.

Study metadata

Study type
Original study
Study category (metadata hint)
Cell or laboratory
Published
2026-08-06
Authors
Dong L, Xing Y, Li X, Xu B, Chen H.
Journal or registry
Not reported
Registry study design
Not reported
Registry enrollment
Not reported
Funding agencies
Not reported in source metadata
Identifiers
DOI: 10.1016/j.bbadis.2026.168398 · PMID: 42562054
First found
Sep 25, 2026
Last found
Sep 25, 2026

Original sources

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